WHAT ARE SARMS?
Selective androgen receptor modulators or SARMs are a novel class of androgen receptor ligands. (The name follows the terminology currently used for similar molecules targeting the estrogen receptor, "Selective Estrogen Receptor Modulators.
They are intended to have the same kind of effects as androgenic drugs but be much more selective in their action, allowing them to be used for more uses than the relatively limited legitimate uses of anabolic steroids.
SARMs provide the ability to design molecules that can be delivered orally, but that selectively target the androgen receptors in different tissues differently. The goal of research in this area is to allow a customized response: Tissues that are the target of the therapy will respond as they would to testosterone; other tissues where undesirable side-effects are produced will not.
SARMs are a synthetic drug that mimics many of the effects of testosterone in muscle and bone tissue, while (hopefully) having a minimal impact on other organs. Thus, the theory is that you can have the perks of steroids with none of the downsides.
Are SARMS safe?
One key characteristic of SARMs is they’re not easily converted by an enzyme called 5-a reductase into DHT, a driver of many unwanted side effects of steroid use.
SARMs are less powerful than regular steroids, they don’t suppress natural testosterone production as heavily, making them easier to recover from.
Yes, they are safe but there are side effects and the more you take, the more side effects you’ll experience.
SARMs aren’t completely free from side effects—they just tend to be minimal at small doses.
Bodybuilders don’t generally take small doses, though, and that’s why they often experience many of the side effects associated with steroid use, including acne and hair loss.
Most popular SARMS
1. Ostarine (MK-2866) - this is one of the most popular SARMs. It helps gain muscles rapidly without nasty side effects. Also, it contributes to bone and tendon formation. What’s more important is that it doesn’t cause any harm to your libido, cognition, or energy. The results of reliable clinical studies support the effectiveness of Ostarine. The duration of the cycle is around 6-10 weeks (recommended daily dose is 10-25 mg).
2. Stenabolic (SR9009) - stimulates the process of burning fat, reduces inflammation, and increases stamina. By using this SARM, you can improve endurance and lose fat at the same time. The recommended duration of the program is 4-8 weeks (20-30 mg).
3. Ligandrol (LGD-4033) – except for increased muscle mass and decreased fat, you can improve bone density without toxic effect on the liver. The recovery process after the cycle is faster if compared to other SARMs. Ligandrol is the best muscle gain amplifier with a half-life from 24 to 36 hours.
4. Andarine (s-4) – is known in a community of bodybuilders because of its ability to build body mass, strengthen and maintain muscles. You can sharply increase endurance and strength using this SARM. The optimal dose is 50 mg daily.
5. Testolone (RAD-140) - this SARM is beneficial because it can help improve endurance and recovery without any prominent side effects. Testolone can be used as an excellent addition to any cycle or used solely. It’s also perfect for long cycles as it doesn’t cause suppression.
6. Nutrobal-677 – increases serum concentrations of IGF-1 and concentration of growth hormone. Nutrobal effectively fights obesity and helps increase lean body mass. The recommended daily dose is 25 mg.
7. Cardarine (GW-501516) – offers incredible endurance benefits. You can get lean easily using Cardarine and increase run times. Extended weight lifting sessions and high energy will enable you to do more work in a gym. Fat loss thanks to increased glucose uptake in muscles is another benefit of this SARM. It has a slight anabolic effect.
8. Epithalone – is a synthetic polypeptide which is analogous to natural Epithalamin produced in the human body. The primary task of Epitalone is to enhance metabolism, regulate levels of gonadotropins and melatonin. Apart from muscle growth, you can resist emotional stress with the help of this SARM. It also acts as an antioxidant, helping keep your body young.
9. Ibutamoren (MK-677) – the drug activates the growth of hormones’ secretagogue and produces a sustainable increase in plasma. It’s essential that the level of cortisol remains the same. It helps increase muscle mass and bone density. Ibutamoren is used to treat bone frailty and obesity as it alters metabolism.
10. S-23 – is a potent SARM, which can help burn fat and gain lean mass. Some bodybuilders consider this SARM number two in the list of SARMs by its potency.
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